News, research, resources, and personal stories about mania, hypomania, manic episodes, and bipolar I disorder

Governor Newsom’s CARE Court, previously limited to schizophrenia, now covers bipolar I disorder with psychotic features under a law that took effect January 1, 2026. A new California law has…
On the evening of January 13, 2026, the Trump administration sent termination notices to roughly 2,000 organizations receiving federal grants through the Substance Abuse and Mental Health Services Administration (SAMHSA).…
Could stigma be the hidden link between bipolar disorder and substance use? A neuroscience student explores a self-reinforcing cycle worth studying.
Cigarettes, lighters, pens, a flashlight, breath mints. During my manic episode I was obsessed with carrying certain objects at all times. Here is why.
During my manic episode I pretended to be homeless, blind, wealthy, and charming. I packed a bag of costumes and believed I was ministering to the world.
Kelly Cole-Duke, 41, boarded a flight without medication during a manic episode. Her story illustrates one of mania’s most dangerous features: the impulse to go. In early May 2026, Kelly…
A study of young people at risk for bipolar disorder found that unstable sleep-wake cycles are connected to mania symptoms through measurable changes in brain wiring. A new brain imaging…
Updated global data shows bipolar disorder affects between 1 and 2.4 percent of the world population, with the majority in low- and middle-income countries lacking access to adequate treatment. An…
From a fatal subway push to a murder sentencing to a coroner’s call for reform, these cases from 2026 show what happens when manic episodes collide with a system that…
Starting in 2027, most Medicaid expansion adults must report 80 hours of monthly work to keep benefits. Exemptions exist for “disabling” mental illness, but the details remain unclear. New federal…
New research links inflammatory markers and mitochondrial dysfunction to the progression of bipolar disorder, pointing to potential new treatment targets beyond traditional mood stabilizers.
Women with bipolar disorder are more likely to be misdiagnosed with depression first. Here is why their symptoms differ and what that means for treatment.
Stress, lost sleep, and substances can all trigger manic episodes in people with bipolar disorder. New research explains why, at the level of brain chemistry.
Lithium has treated bipolar disorder for more than 70 years. Here is how it works in the brain, what the side effects are, and why doctors still prescribe it first.
During my manic episode I merged with the universe and felt total unity with all things. Was it psychosis or revelation? I am still not sure.
Ted Turner, who died May 6 at 87, lived with bipolar disorder for decades. His manic energy helped build CNN, but the lows nearly destroyed him.
Mania and hypomania share many symptoms, but the differences determine your diagnosis and treatment. Here is what sets them apart and why it matters.
I knew my hypomania was escalating. I estimated it at 50 percent. I thought awareness meant control. I was wrong.
Living with bipolar I taught me to blend in everywhere. The problem is I stopped knowing which version of me was real.
During my manic episode I promised trips, businesses, and a life I could never deliver. The hardest part was watching people believe me.
During mania my phone felt impossibly slow. I rebooted it over and over. The problem was never the phone. It was my brain running at a speed the world could…
A study of people with major psychiatric disorders found that drinking up to four cups of coffee daily was linked to longer telomeres, suggesting slower biological aging by about five…
Up to 60 percent of people with bipolar I will develop a substance use disorder. New research explains why the two conditions fuel each other and what works for treatment.
Alzamend Neuro’s AL001 delivered more lithium to the brain in less time than standard lithium carbonate in a Phase 2 trial, with a bipolar I study now underway at Mass…
The BD2 network just released the largest multimodal psychiatric dataset ever created, with data from 615 participants including brain scans, wearables, and biomarkers.
A Penn Medicine study found that five days of accelerated theta burst brain stimulation dramatically reduced depression scores in treatment-resistant bipolar patients.
Johns Hopkins researchers used brain organoids grown from patient cells to identify bipolar disorder with 92% accuracy, opening the door to personalized treatment testing.
The first quarter of 2026 brought a new FDA-approved drug for bipolar I, a smarter lithium delivery system, and psilocybin reaching phase 3 trials for treatment-resistant depression.
Mixed episodes affect one-third of people with bipolar disorder, combining mania and depression simultaneously. Experts say they carry the highest risk and are often missed.
Mania Insights reports news, scientific research, helpful resources, and real-life experiences about mania and manic episodes. Mania Insights aims to break the silence and reduce the stigma, empowering individuals and families to better understand the bipolar I condition and thrive.
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